PCSK9-antibodies fail to block PCSK9-induced inflammation in macrophages and cannot recapitulate protective effects of PCSK9-deficiency in experimental myocardial infarction

Rauterberg S, Härdtner C, Hein J, Schrepf P, Peyronnet R, Koentges C, Vico TA, Ehlert C, Dufner B, Lindner D, von zur Mühlen C, Wolf D, Westermann D, Hilgendorf I, von Ehr A. PCSK9-antibodies fail to block PCSK9-induced inflammation in macrophages and cannot recapitulate protective effects of PCSK9-deficiency in experimental myocardial infarction. Front Cardiovasc Med 2025/11:1463844. doi: 10.3389/fcvm.2024.1463844.

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